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However, we could identify Cys115 and 174 as putative targets in human GSTM2

5,6 For example, free radicals play a role in detoxification of xenobiotics by oxidizing enzymes, in killing of microorganisms by macrophages and cytotoxic lymphocytes, and in the generation of prostaglandins and leukotrienes, which activate oxygenases (e.g., cyclooxygenases and lipoxygenase) and thus act as modulators of the inflammatory response

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The key is maintaining consistent weekly intervals between doses to ensure stable drug levels

On the other hand, Jolink and collaborators showed that IL-17 provides a protective immunity by decreasing lung fungal burden in a murine infection model (126)

[DOI] [PubMed] [Google Scholar] 219.Roberts J.D., Fineman J.R., Morin F.C., Shaul P.W., Rimar S., Schreiber M.D., Polin R.A., Zwass M.S., Zayek M.M., Gross I., Heymann M.A., Zapol W.M., Thusu K.G., Zellers T.M., Wylam M.E., Zaslavsky A