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Prior guidelines have recommended trying lifestyle interventions before beginning medication, but this new guidance recommends considering these medications as a first-line treatment option for eligible patients

Nature 450 , 383387 (2007) Hjorth, S

Supplemental Material This article contains supplemental material located online at Supplementary Material Acknowledgments The authors thank Dr Timothy Ryder from Biological Communications Limited (London, United Kingdom) for writing and editorial assistance, funded by Allergan Aesthetics, an AbbVie company

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