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The misuse of GLP-1 drugs without clinical oversight can lead to severe health complications

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The Pentelute Lab aims to invent new chemistry for the efficient and selective modification of proteins, to hijack these biological machines for efficient drug delivery into cells and to create new machines to rapidly and efficiently manufacture peptides and proteins.

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Researchers at the Lunenfeld-Tanenbaum Research Institute, part of Sinai Health, have discovered a gut-brain-immune network and posit a new gut-brain glucagon-like peptide 1 (GLP-1R) that controls inflammation across the body, a discovery which holds promise for understanding and treating metabolic diseases