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Enter novel therapeutics like CCT217: By driving beige fat activation and functional thermogenesis, these agents could rapidly improve insulin sensitivity, ApoB/TG, hsCRP, hepatic fat, and microvascular functioneven before the scale moves

In this study, human umbilical vein endothelial cells (HUVECs), exposed to palmitic acid (PA) to induce endothelial dysfunction, were incubated with metformin, liraglutide or their combination