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Others have reported greater prevalence of risk factors such as obesity, tachycardia at rest, HTN, high total and low-density lipoprotein (LDL) cholesterol and changes on electrocardiogram in SLT users41

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Bupropion increases smoking cessation rates compared to placebo or control.(132,147) Two studies of smokers hospitalized with acute coronary events did not find increases in smoking cessation in smokers who received bupropion versus placebo.(148,149) Bupropion treatment does not appear to be associated with an increase in major adverse cardiovascular events.(129) Contraindications to use of bupropion include seizure disorder or having a high risk for seizure

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