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This comprehensive review critically evaluates recent advances in BBRs anti-obesity pharmacology through three lenses: (1) preclinical and clinical evidence from randomized controlled trials, (2) molecular mechanisms underlying metabolic regulation, and (3) innovative strategies for pharmacokinetic optimization

Investigations focus on its effects in weight loss, glucose regulation, and energy balance, showing potential therapeutic benefits for obesity, type 2 diabetes, and other metabolic disorders in experimental models

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It's a fillip for new Novo Nordisk chief executive Mike Doustdar, who took the helm last year with a clear remit to defend the GLP-1-based weight loss and diabetes business from rivals like Eli Lilly, as well as knock-off versions of semaglutide that sidestep the company's intellectual property (IP).

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