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However, long-term treatment with vitamin E has been associated with increases in all-cause mortality and the risk for prostate cancer [2527], suggesting the need to evaluate the efficacy and safety of this agent

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The study identified increased proportions of pro-inflammatory and mesenchymal fibroblast subpopulations, elevated p16 protein and SA--galactosidase-positive cells, and enhanced SASP gene expression in keloid tissue

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This can lead to health issues like megaloblastic anemia

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