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This can lead to establishing a new weight set point

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GLP1 acts through a Gproteincoupled receptor expressed on pancreatic beta cells and neurons of the central and peripheral nervous system (Kanoski et al., 2011

Patients with controlled diabetes (excluding type 1 diabetes mellitus) who are not experiencing diabetic ketoacidosis

4, 2025 from MedlinePlus

However, this creates a complex situation: while GLP-1 agonists might improve PCOS symptoms through weight loss, certain ones (like exenatide, lixisenatide, and tirzepatide) could potentially interfere with the oral contraceptives being used to manage the condition
