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At study entry, patients in study 1 were not treated with oral antihyperglycemic agents
doi: 10.1210/jc.2015-2765 38 OuchiNWalshK
Kissileff HR, Pi-Sunyer FX, Thornton J, Smith GP
A newer version of phentermine (combining phentermine with topiramate in one pill) was approved for chronic weight management in adults and kids down to age 12 in 2012 and marketed as Qsymia
Their brand-name pens can go much higher, up to roughly $2,000/mo for something like Zepbound or Mounjaro
