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GLP-1 receptors in the pancreas enhance glucose-dependent insulin secretion, meaning insulin release increases when blood glucose rises, but not when it is already normal or low

Are the results permanent

Aim for at least eight 8-ounce glasses of water per day, or about 2 liters

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doi: 10.2337/dc12-1925 [DOI] [PMC free article] [PubMed] [Google Scholar] Schmidt HD, Mietlicki-Baase EG, Ige KY, Maurer JJ, Reiner DJ, Zimmer DJ, Van Nest DS, Guercio LA, Wimmer ME, Olivos DR, De Jonghe BC, Hayes MR

The clinical science behind GLP-1 receptor agonists as a drug class is separately and independently robust