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The search operation, lasting two days, is the latest in the MHRAs ongoing work to tackle the illegal trade in weight loss medicines

The medication slows gastric emptying and may affect absorption of oral medications, requiring additional contraception for 4 weeks after initiation and dose increases

These medications mimic a natural hormone produced in the intestines, helping to lower blood glucose, boost insulin production, and slow down digestion

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Work in animals provides evidence for each of these putative pathways, supporting that ghrelin can act locally in the hypothalamus (i.e., paraventricular nucleus, arcuate nucleus), NTS, and potentially, in the hippocampus and VTA (Perello et al., 2019)