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Development 143(13):22492260 Patan S et al (1992) Intussusceptive microvascular growth: a common alternative to capillary sprouting

The peptides molecular structure prevents it from crossing the blood-brain barrier and accessing hypothalamic regions responsible for hunger signaling, satiety, and feeding behavior

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In one study investigating the early effects of treatment discontinuation in choroidal neovascularization, it was noted that anti-VEGF treatment enhanced closure of terminal vessels and that treatment caused increased flow within the trunk during choroidal neovascularization reactivation 89