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To mitigate this, initial dosing of exenatide usually starts low (5 g BID) then increases to 10 g BID after a month

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DPP4 in Diabetic Nephropathy Research suggests that DPP4 may play a role in the receptor axis for advanced glycation end products (RAGE), which is crucial for the development of diabetic nephropathy

Liu S, Zhang L, Li S