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NNMTi is a NAM analog that inhibits NNMT activity by competing with NAM (Parsons and Facey, 2021)

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reported the first NNMT bisubstrate inhibitor VH45 ( 13 ), displaying an IC 50 value of 29.2 4.0 M

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This typically improves as treatment continues and should be discussed with your healthcare professional if persistent

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