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doi: 10.3949/ccjm.90a.22096

Through the middle of a protocol, many report less pain, improved range of motion, and a gradual return of activities that had been off-limits

Older adults may see slower initial weight loss but more durable glucose control, while people with higher baseline weight often experience earlier appetite suppression due to greater GLP-1 receptor sensitivity

Pi-Sunyer X

The cohort comprised patients over 20 years old who were newly treated with glucose-lowering drugs between 1 January 2013 and 31 December 2021, and followed until 30 September 2022

Retatrutide is one of the most promising agents in the current pipeline for obesity pharmacotherapy, but it is essential to interpret the available evidence with appropriate context