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One more thing

Always verify current approvals for these GLP-1 medications with your prescribing physician

General principles for restarting GLP-1 medications include: Adequate oral intake : You should be tolerating a normal diet (or your usual post-operative diet plan) without significant nausea or vomiting Resolution of post-operative ileus : Normal bowel function should have returned, particularly after abdominal or pelvic surgery Stable clinical condition : Any post-operative complications should be resolved, and you should be recovering as expected Medical team approval : Always confirm with your surgical team or GP before restarting If you've been off a GLP-1 medication for several weeks, your doctor may recommend re-titrating the dose (starting at a lower dose and gradually increasing) to minimise gastrointestinal side effects when restarting

Another area of attention is cardiovascular safety

And unfortunately, this combination is not uncommon on GLP-1 medications, particularly during the first few weeks of treatment or after dose increases

Further, the CVOTs in general also suggested a potential benefit of GLP-1 RAs on HF, positioning GLP-1 RAs as another advanced option alongside SGLT2 inhibitors in the otherwise sparse treatment armamentarium for especially HFpEF