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FEBS Letters 446: 223227
Labs, symptom tracking, and frequent check-ins guide everything
Unlike whole-body Gclc KO mice, liver-specific Gclc L-KO mice did not have any difference in survival or body weight following Gclc deletion (Fig
Specifically, cGAS recognizes cytoplasmic DNA to form dimers that catalyze cyclic GMP-AMP production, subsequently activating the STING protein and initiating type I interferon responses (108)
10.1016/0016-5085(92)91186-8 [DOI] [PubMed] [Google Scholar] Trusolino L., Bertotti A., Comoglio P
Nature Reviews
