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Semaglutide and tirzepatide represent new treatment modalities for type 2 diabetes mellitus (T2DM) and obesity, expanding the range of glucagon-like peptide-1 (GLP-1) receptor agonists

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Acid suppression Proton pump inhibitors (PPIs): omeprazole, pantoprazole H2 receptor blockers: ranitidine, famotidine 3

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### Funding Statement No funding ### Author Declarations I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained

Methods: The Plan-Do-Study-Act (PDSA) model was used in the design of this QI project