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Furthermore, the more recent observational data suggesting that the combination of high folate and low vitamin B-12 is associated with the worsening of both clinical outcomes and elevations in functional biomarkers of vitamin B-12 (23, 40, 41) imply that depletion of holoTC is attained even without stimulating hematopoiesis

doi: 10.1039/D1TB01290H, 237 YukselB.DoganM.BoyaciogluO.SahinM.Orenay-BoyaciogluS

PMID: 71

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The case has been referenced in legal discussions as a cautionary example for the legal status of research peptides in 2026

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