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MPT Protein nitration, such as nitrotyrosine formation, is a major stimulus for formation of the mitochondrial membrane permeability transition (MPT)

Jiang W, Li Y, Zhao Y, Gao Q, Jin Q, Yan C, Xu Y

EHA 2023, 2023

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43 While adenosine signaling via ADORA2b signaling has been previously linked to acclimatization to high altitude hypoxia by favoring energy metabolism to boost oxygen off-loading, 4 our findings here underscore the critical role of purinergic signaling in maintaining RBC metabolism during refrigerated storage