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doi: 10.1210/en.2009-0195

B12 plays a crucial role in the conversion of carbohydrates to glucose, which cells use for energy

The NMDAR hypofunction leads to cortical oxidative stress, GSH deficiency, and decreased activity of the thioredoxin/peroxiredoxin system through transcriptional control of several critical antioxidant genes [24]

The lack of effective small-molecule drugs to disrupt interactions between proteins has led to PPIs being viewed as challenging or undruggable targets [10]
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