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Dihexa was also predicted to be 22.59% unbound to plasma proteins in circulation, thus making it available for distribution into the tissues

Dried Loquat Fruit Extract Containing Chlorogenic Acid Prevents Depressive-like Behaviors Induced by Repeated Corticosteroid Injections in Mice

Am J Physiol Regul Integr Comp Physiol 292(1):R18-36

However, 20% of men, who eventually had a PSA response to chemotherapy, had an initial rise in their serum PSA and the median time to PSA response was 44 days (range 2668 days), so most patients received two or more cycles of treatment before their response status could be ascertained (Tannock et al, 2004)