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Tissue Collection Mouse ileum was collected from female C57BL/6NTac mice (approximately 25 g body weight), and specimens from human terminal ileum were taken during colonoscopy as previously detailed (13)

Binding specificity and signal transduction of receptors for glucagon-like peptide-1(7-36)amide and gastric inhibitory polypeptide on RINm5F insulinoma cells

139 Although generally well tolerated, meta-analysis of 14 clinical trials suggests that long-acting GLP-1RAs (eg, semaglutide, tirzepatide) are associated with lower rates of gastrointestinal side-effects, particularly nausea and vomiting, compared to short-acting agents (Table 2)

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