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Using an integrated ligand and structure-based virtual screening pipeline, explicitly combining complementary ligand-based descriptors, multi-fingerprint similarity, electrostatic similarity, pharmacophore modeling, and multi-conformation docking under a consensus-driven selection strategy, we were able to identify three chemically distinct classes of GLP-1R agonist candidates: GQB47810, a non-peptidic molecule

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Soaring use of these medications for weight loss is shifting demand, including for packaging manufacturers that serve pharma and food customers

I hope my friends in the compounding community call out this type of behavior and if I were one of the manufacturers of current approved GLP-1s (Novo Nordisk, Eli Lilly and Company, etc), I would explore legal action against any company who is blatantly abusing #drugshortage loopholes to engage in manufacturing and not #compounding