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Shisha is seen as a popular social activity, especially among youths who view this as a harmless recreational activity

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Short-term exposure of 2-month-old mice (6h/day x 5 days/wk x four or 8 weeks) to a mixture of sidestream/mainstream cigarette smoke impairs brain insulin signaling and induces the accumulation of neuropathological proteins (La Maestra et al., 2011), markers of neuropathology frequently observed in MCI and patients with dementia (Lovell and Markesbery, 2007

The exact cause of canker sores is not known

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