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Conclusions: For most people with COPD, studies show that the harms from using ICS outweigh the benefits

In doing so, this review makes important and meaningful contributions to the ongoing efforts of combating the global health crisis posed by tobacco use, all while emphasizing the need for multifaceted strategies that include not only public health measures and educational efforts, but also innovative research that focuses on understanding and mitigating the biological mechanisms underlying smoking-related health conditions

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(2017) 28 Suppl 1:S7481