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Smoke or soot: Could indicate blocked vents, a cracked heat exchanger, or incomplete combustion especially in gas furnaces

PMID 17666709
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These include respiratory ailments, cancer of the lungs, oral cavity, esophagus, pancreas and colon, atherosclerotic vascular disease, and stroke
But despite all the cultural weight it carries, the core mechanism hasnt changed

Keep in mind that everyone has a unique metabolism, and that can also affect the kind of high you achieve