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At least 250 of those chemicals are known to be harmful (and 69 can cause cancer)
VG is also one of the least reactive substances in the world, making it great for those who are sensitive to inhaling propylene glycol

A 1978 Philip Morris report noted: Extremely high pesticide residue levels have been found in all samples submitted by PM-Australia, eg
Despite this, only around 3% of smokers who attempt to stop do so after six months
Hepatogastroenterology 31:3034 Bonaz B, Sinniger V, Pellissier S (2017) The Vagus Nerve in the Neuro-Immune Axis: Implications in the Pathology of the Gastrointestinal Tract

Now, researchers are coming to understand the hazards of vapes themselves