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Erratum in Lancet 2019, 394, e1

Skin sometimes loses a bit of stretch, causing sagging

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Sci Rep 11:10096 Shah SJ, Sharma K, Borlaug BA et al (2024) Semaglutide and diuretic use in obesity-related heart failure with preserved ejection fraction: a pooled analysis of the STEP-HFpEF and STEP-HFpEF-DM trials

GLP-1 Rash A GLP-1 rash may appear as small red patches, raised bumps, or itchy spots at the injection site

Notable for: Multi-database design (improves generalizability) Active comparator framework Emphasis on short-term safety with acknowledgment of need for longer follow-up Diabetes Care Retrospective Cohort Evaluated thyroid tumors (broader outcome than confirmed malignancies) and found no increased risk with GLP-1 RA exposure in type 2 diabetes patients initiating second-line treatments