earliest tobacco use MarketingModule Earliest Known Use Of Tobacco

Drug misuse: Date this section was last reviewed 09/07/2013 (PL)

25 , the LD50 values were extrapolated assuming linear behaviour (as no other information on dose-response is available) to BMDL10 values

Other signs of toxicity include increased saliva production, diarrhea, increased activity and agitation followed by extreme depression, difficulty walking, seizures, tremors, and increased heart rate

All incidents of accidental exposure should be reported immediately

Drugs and alcohol could also interfere with existing prescribed medication

13 Women are at greater risk than men when consuming alcohol and drugs, as their bodies metabolize substances at rates different than men, causing them to experience stronger effects across shorter periods of time