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The ROS is a single summary of the effect of smoking on the outcome, with higher positive ROSs corresponding to stronger and more consistent evidence and a higher average effect size of smoking and a negative ROS, suggesting that, based on the available evidence, there is no significant effect of smoking on the outcome after accounting for between-study heterogeneity

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For it to function optimally, it needs a steady supply of nutrients and oxygen delivered through blood circulation

Based on the research so far, its clear that nicotine can have some negative effects on muscle repair and protein synthesis