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The subjects were in the Cambridge Study in Delinquent Development, comprised of 411 boys who were born around 1953 and living in working-class urban neighborhoods of London

Other author conflicts of interest are noted in the manuscript

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PPRs families include Toll-like receptors (TLRs), purinergic receptors (e.g., P2X and P2Y), cytosolic nucleotide-binding oligomerization domain (NOD)-like receptors (NLRs), and receptor for advanced glycation end products (RAGE)

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