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Both hormones were analyzed using radioimmunoassay method with published modifications to the manufacturers protocol [30]

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Accordingly, the results from our study let us hypothesise that CSC could be responsible for two main steps in the atherogenic process: (i) CSC induces endothelial cell death and therefore it could be responsible for endothelial damage on the vessel wall and (ii) CSC triggers the initiation of an inflammatory response through induction of necrotic cell death

doi: 10.1371/journal.pone.0180475 155 FairleyASMathisKW

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