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LINK Wartmann CT, Loukas M, Tubbs RS: Letter to the editor, on Arcuate Line

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The most obvious is that allowing consumers access to safer sources of nicotine can drastically reduce sales of cigarettes

So far, only one such device -- made by one of the world's largest tobacco companies, Philip Morris International -- has been authorized by the U.S

Overnight, smokers become resensitized to the drug, tolerance diminishes, and the cycle begins anew on the next day (Figure 7)

Moreover, while the Revised Health Promotion Law will permit tobacco consumption in restaurants and shops valued at less than 50 million yen and with floor space less than 100m2, provided they have the proper signage, the Tokyo Metropolitan Ordinance to Prevent Exposure to Second-Hand Smoke makes no such exceptions