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In STZ-injected rats, chronic administration of silodosin attenuated the diabetes-associated increases in bladder capacity and residual urine (Yonekubo et al

doi: 10.3390/ijms241713381

Side effects like nausea, vomiting, diarrhea, or constipation are common early on but often improve with proper management
This sustained trajectory could reshape formulary positioning if the safety profile holds

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