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A little-known tobacco technology, Heat-not-Burn (HNB), has the potential to slash smoking-related death and disease by appealing to the millions of smokers who've failed to quit using e-cigarettes and traditional nicotine-replacement therapies

The control and CDP-treated groups had similar beta-endorphin levels, demonstrating the compounds potential to restore hormonal balance without causing abnormal hormonal reactions

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It is important to note that homemade cigarettes can be even more deadly than manufactured ones, as they lack filters and other industrial checks that can at least prevent some of the worst harms of cigarette smoke

A chronic study showed that smokers who switched to IQOS for six months had significantly lower eCO, within the range of non-smokers 93

While a majority of vapers in this study opposed this policy, and many vapers would not be willing to switch to available flavours, there was considerable variability in their responses