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T3: 10 minutes after intervention

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The added amounts are sufficient to produce robust cooling sensations, with some brands having more cooling activity than their menthol equivalent cigarettes. When Californias menthol ban was enacted in December 2022, the big tobacco companies, RJ Reynolds and ITG, introduced non-menthol cigarette brands as menthol substitutes, with very similar packaging and marketing strategies as their menthol cigarette brands

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To control for false positives resulting from multiple hypothesis tests inherent to RNA-seq experiments, p -values were adjusted via the BenjaminiHochberg procedure to control the false discovery rate (FDR)