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Thousands of young people start smoking every day, and the tobacco industry spending on advertising has increased

Prolonged nicotine consumption/smoking reduces active receptors (unstimulated receptors) and dopamine release that stimulates the increase of smoking packs to recover their pleasure [72]

10.3389/fcell.2021.628157 209 SidletskayaK.VitkinaT.DenisenkoY

doi: 10.1038/sj.mp.4001774

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