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While clinical trials suggest ENDS may increase smoking abstinence over NRT, real-world effectiveness and long-term safety require further study

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Measures That Have Been Most Effective Both countries have implemented similar strategies to reduce smoking, but some measures have had a particularly strong impact: United States: Public Health Campaigns: The CDCs Tips From Former Smokers campaign has been highly effective, motivating over 5 million Americans to attempt to quit smoking between 2012 and 2018

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Those who report more barriers to smoking cessation while using substances or alcohol report low confidence in the ability to change their tobacco-smoking behaviour (McHugh Reference McClure, Baker and Hood2017)