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In a pilot trial evaluating 104 amnestic MCI and early-stage AD patients, 20 IU and 40 IU doses of intranasal insulin improved Alzheimers Disease Assessment Scale-Cognitive subscale (ADAS-Cog 12) scores compared to placebo-treated patients, with improvements in delayed recall observed 2 months following cessation of treatment in the 20 IU group

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If you develop severe constipation lasting more than a few days, contact your healthcare provider before adjusting either medication
Both GIP and GLP-1 play roles in regulating food intake by stimulating neurons in the brains satiety center

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