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Description
p53 efficiently suppresses tumor development in the complete absence of its cell-cycle inhibitory and proapoptotic effectors p21, Puma, and Noxa
The depletion of senescent cells in aging mice delayed age-related morbidity and decreased the incidence of tumorigenesis and cancer-related death [33]
Oxid Med Cell Longev 2022, 2022:3087198
It further addresses the interaction between p53 and vitamin D receptor (VDR), which may aid in suppressing skin carcinogenesis
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