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These studies evaluated several potential factors associated with the reductionsuch as tax hikes, stricter smoking laws, or other nicotine productsand concluded the introduction of HTPs was the most likely explanation for the sharp drop in cigarette sales in those years

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Neurofibrillary tangles (NFTs) are intracellular aggregates of hyperphosphorylated Tau proteins and are hallmarks of AD and other neurodegeneration diseases 113

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