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Surprisingly, this trend was reversed during the COVID-19 pandemic in many markets, including the U.S., which saw a growth of 2.3% in sales volumes in 2020 compared to 2019

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ECs have inherent toxicity and unknown long-term health effects

Both product categories lean on the rapid delivery of active compounds

Similarly, mice exposed to e-cigarette aerosol with nicotine and tobacco flavouring had increased markers of oxidative stress in lavage fluid and lung homogenate, including MDA and protein carbonyl levels, compared to vehicle control [79]