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Methods Cross-sectional analysis of whole blood and sputum RNA-sequencing data from 8 smokers, 9 e-cigarette users (e-cigs) and 4 controls

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doi: 10.1177/17423953231213853 4
Pyrazines are deliberately added to enhance the sensory experience and reinforce addiction mechanisms, making it more challenging for tobacco users to quit or avoid relapse
Richthoff J, et al

Stopping smoking is no different