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10.1038/nm1196-1254 58 ShanY.GaoX.ZhaoK.XuC.LiH.HuY.et al (2023)

GLP-1s lower pro-inflammatory cytokines involved in psoriasis

D., Satylganova, A., Skovgaard, D., & McGowan, B

Pathogenesis and Negative Impact of Diabetes Mellitus in Liver Transplant Recipients The global increase in diabetes mellitus has led to a substantial rise in its prevalence among liver transplant candidates

WeightWatchers, which was first started in 1963 and instituted in strip malls across America, has long been touted by its supporters (including Oprah Winfrey herself, who owns stake in the company) as an easier way to lose weight, while avoiding the stigma and temptation of crash diets and weight loss pills

GLP-1R activation of neuroprotective pathways in neurons, microglia and astrocytes has also been reported: improvements in overall cognition, learning and motor function potentially associated with GLP-1RA administration in Alzheimers disease and Parkinsons disease may be mediated not only by their amyloid pathology-ameliorating properties (A, tau and -synuclein), but also the suppression of Ca 2+ deregulation and endoplasmic reticulum stress, anti-inflammatory activity, blockage of oxidative stress, mitochondrial dysfunction and apoptosis pathways, enhancements in the neuronal insulin sensitivity and energy metabolism, functional improvements in autophagy and mitophagy, elevated brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor synthesis, and neurogenesis 36