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GLP-1 gallbladder risk is gaining attention in 2026

Anal fissures are tears that occur in the membranes on the inside and around the anus

Subgroup analysis for treatment durations6 months indicated a higher WL in the GLP-1RAs group (SMD=0.79, 95% CI 0.25 to 1.34)

Retatrutide is a triple receptor agonist activating GLP-1R, GIPR, and GCG-R pathways to reduce appetite, improve insulin secretion, and support metabolic health

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President Trump recently announced a deal with drugmakers to expand access to GLP-1 drugs to Medicare patients starting in 2026
