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Approval could open the door to more drug development in an area that addiction researchers say is sorely needed

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[21] The smoking age was raised to 21 by the Ohio General Assembly in 2019 five months prior to the federal Tobacco 21 law

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In addition, it highlights the interference caused by tobacco products in Wnt signaling, PI3K/Akt/mTOR, JAK-STAT, and other important pathways