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In a key paper from 2012 it was the largest and longest-running study to date, testing 1,037 people at age 13 and 38 scientists at Duke University found a dramatic drop in intelligence among long-term marijuana users suggestive of a neurotoxic effect of cannabis on the adolescent brain, they wrote in PNAS

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Trends in smoking initiation in europe over 40 years: a retrospective cohort study