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Nicotine replacement therapy (NRT) can be effective in reducing cravings and the severity of withdrawal symptoms

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The absence of a cardiovascular stimulus from nicotine-free vaping is significant, as people using other forms of nicotine delivery (smokers, NRT, dual use vapers and smokers) all had similar levels of circulating nicotine compared to nicotine-free vapers [88], though others report higher levels in smokers than vapers [82]

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Both studies analyzed consecutive waves of the longitudinal Population Assessment on Tobacco and Health (PATH) survey in adults

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