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Exosomes Exosomes are vesicle-like structures with a diameter of 40160 nm released after the fusion of intracellular multivesicular bodies (MVBs) with the cell membrane

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Initially, in the free state, FOXO4-LRI exhibited secondary chemical shifts characteristic of an intrinsically disordered peptide

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This is cleaved into functional units by the three proteases: P1 protease (1 cleavage site), helper-component protease (1 cleavage site) and TEV protease (7 cleavage sites)

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The antioxidant role of vitamin C may explain the observed low plasma levels of vitamin C in adults with AD

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The capsules were implanted subcutaneously via a small skin incision, with 3 capsules per mouse (5-week-old female nu/nu mouse)

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Russian research background

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